First of all, science that hasn't been replicated and peer-reviewed (which is to say science that hasn't been publicly verified) isn't science - it's speculation. What's FAR more important, though, is that EPA regulations need to be based on the Constitution. The ultimate authority to which all government bodies are accountable, regardless of whether or not their policies are based on science, is the Constitution. That's the primary concern, and if it isn't met then having a scientific basis is irrelevant. But you can't say that, can you? Because then there wouldn't even be an EPA at all.